Preimplantation genetic diagnosis (PGD) according to medical ethics and medical law

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Preimplantation Genetic Diagnosis (PGD)

Preimplantation genetic diagnosis (PGD) is a reproductive technology used with an in vitro fertilization (IVF) cycle to increase the potential for a successful pregnancy and delivery. The most common applications for PGD include testing for extra or missing chromosomes (aneuploidy screening), familial structural chromosome rearrangements, and diagnosis of genetic disease in couples of increased...

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Preimplantation genetic diagnosis (PGD) for heritable neoplasia.

UNLABELLED Especially applicable for heritable neoplasia, preimplantation genetic diagnosis (PGD) is possible for any Mendelian disorder whose gene has been localized, whether the molecular basis is known or not. METHODS AND RESULTS PGD requires DNA from gametes (oocytes) or embryos before 6 days postconception, when implantation occurs. Approaches include 1) polar body biopsy, 2) blastomere ...

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Preimplantation Genetic Diagnosis (PGD) for chromosome rearrangements

• Chromosome rearrangements include Robertsonian and reciprocal translocations (the most common form of chromosome abnormality in humans, present in approximately 1 in 500 individuals), periand paracentric inversions, interand intra-chromosomal insertions, deletions, duplications, and complex chromosome rearrangements (CCRs). • In all cases presenting for PGD, the risk of viable abnormality sho...

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Extending preimplantation genetic diagnosis: medical and non-medical uses.

New uses of preimplantation genetic diagnosis (PGD) to screen embryos prior to transfer raise ethical, legal, and policy issues that deserve close attention. Extensions for medical purposes, such as to identify susceptibility genes, late onset disease, and human leukocyte antigen (HLA) matching, are usually ethically acceptable. Whether embryo screening for gender, perfect pitch, or other non-m...

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Bach to the future: response to: Extending preimplantation genetic diagnosis: medical and non-medical uses.

Professor Robertson sketches an elegant framework for policy evaluation and regulation of the use of preimplantation genetic diagnosis for various medical, medical related, and non-medical purposes. In criticism of his position, I argue that the distinction between policy and ethics upon which his argument relies is highly unstable, and the approach taken to ethical evaluation of particular par...

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ژورنال

عنوان ژورنال: Journal of the Turkish German Gynecological Association

سال: 2011

ISSN: 1309-0399,1309-0380

DOI: 10.5152/jtgga.2011.72